As Nigeria marks World Immunization Week for 2021 celebrated from April 24th – 30th every year, it is important to highlight the use of vaccines in mitigating vaccine preventable diseases (VPDs) and to measure the progress of Nigeria’s journey for self-reliance. According to the World Health Organization (WHO), the primary objective of the week is to emphasize the value of vaccines in preventing diseases that were hitherto perceived as life-threatening. This World Immunization Week seeks to highlight the importance of vaccines as a “public good that saves lives and protects health” whilst also allowing development. The theme of 2021 is “Vaccines bring us closer”. This theme seeks to illustrate how vaccines, by preventing disease, can bring us closer to global health goals of eradicating vaccine preventable diseases as well as furthering health equity through universal immunization coverage.